Studies
Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation - ADVANCE
ADVANCE aims to determine the effects of more intensive blood pressure lowering and glucose control on the risks of complications in patients with type 2 diabetes. The study is a factorial, multicentre, randomised controlled trial. 11,140 participants have been recruited and randomised...
Andhra Pradesh Rural Health Initiative - APRHI
The APRHI Collaboration works to improve health status, prevent and manage non-communicable disease, prevent premature death, and enhance access to health services for the people of rural Andhra Pradesh. We aim to achieve this through the design, implementation and evaluation of affordable and sustainable interventions that can be incorporated in the existing primary health care infrastructure of rural areas. Priority interventions will be proposed...
Blood Pressure Lowering Treatment Trialists Collaboration - BPLTTC
This study aims to provide reliable evidence about the effects of different classes of blood pressure lowering drugs on cardiovascular mortality and morbidity in a variety of patient groups. Methods used was a series of prospective overviews (meta-analyses)...
Clinical Pathways in Acute Coronary Syndromes in China Study - CPACS
The overall objective of this project is to develop, implement and evaluate clinical pathways for the management of acute coronary syndromes (ACS) in tertiary and non-tertiary centres in China. The objective of Phase 1 is to reliably document management practices relating to ACS in China...
Electronic Decision Support Study
The overall objective of this project is to test the feasibility of a novel electronic decision support (EDS) tool designed to increase the appropriate use of guidelines for the management of cardiovascular risk in General Practice in Australia...
Heart Outcomes Prevention Evaluation: SOLARIS Study of Lipid Modification and Blood Pressure Reduction in People at Average Risk - HOPE-3
The HOPE-3 trial will evaluate the benefits of combined cholesterol and blood pressure lowering therapies in reducing cardiovascular risk in a wide group of people without vascular disease.
Perindopril Protection Against Recurrent Stroke Study - PROGRESS
PROGRESS aims to dcetermine the effects of an angiotensin converting enzyme (ACE) inhibitor-based blood pressure lowering regimen on the risk of stroke among patients with a history of cerebrovascular disease. Secondary aims include investigation of the effects of treatment on other major outcomes and investigation of the causes of stroke. PROGRESS was a randomised, double-blind, placebo-controlled trial in which 6,105 participants with stroke or TIA were randomised...
Programme to Improve Life and Longevity Pilot Study - PILL
A polypill - containing several medications in one, fixed dose tablet - may help reduce the cost and complexity of reducing the risk of cardiovascular events such as heart attacks and strokes in people at risk of having them.
The Guidelines Adherence with the Polypill Study - GAP
GAP is a randomised controlled trial of fixed dose combination medication (Polypill) versus usual care for improved adherence to indicated pharmacotherapy among individuals at high risk of a cardiovascular event.