Fetal-Origins Overviews

Aims:

To investigate the strength of evidence for the fetal-origins hypothesis of adult disease that proposes that impaired fetal and neonatal growth is associated with increased risk of morbidity and mortality in adult life.

Methods:

Meta-analyses of all studies that have reported on the associations between size at birth with subsequent cholesterol, diabetes, and coronary heart disease.

Status/Results:

New analyses of the associations of birth weight with cholesterol have been published in the Journal of the American Medical Association. Data collection for the analyses of the association between birthweight and coronary heart disease has been completed and preliminary analyses have begun with publication of results expected in 2007.

Publications:

fetal origins overviews publications

Institute Investigators:

Collaborators: