Figure 3. Comparisons of active blood pressure lowering regimens 
based on different drug classes

Figure 3: Effects of blood pressure lowering regimens based on different drug classes on the risks of major vascular outcomes and death

Footnotes
Abbreviations - ACE-I, angiotensin converting enzyme inhibitor-based regimen; CA, calcium antagonist-based regimen; D/BB, diuretic- or beta-blocker-based regimen; mmHg, millimetres of mercury; 95%CI, 95% confidence intervals. 1. Overall mean blood pressure difference (systolic/diastolic) during follow-up in the group assigned the first-listed treatment compared to the group assigned the second-listed treatment, calculated by weighting the difference observed in each contributing trial by the number of individuals in the trial. The positive values indicate a higher mean follow-up blood pressure in the first-listed treatment group compared to the second-listed treatment group.